Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734946 | 0.82 | LMNA (0.58) | LMNAMAPTNPSR1KDM4EHTT | |
| SCHEMBL3821794 | 0.81 | OPRM1 (0.39) | LMNAMAPTNPSR1KDM4EHTT | |
| SCHEMBL3059109 | 0.80 | ACHE (0.39) | LMNAACHEOPRM1CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL3064216 | 0.79 | ACHE (0.39) | LMNAACHEOPRM1CHRM1CHRM3 | |
| SCHEMBL4738981 | 0.79 | LMNA (0.41) | LMNAACHEOPRM1NR1H4CHRM1 | |
| SCHEMBL3064159 | 0.79 | CHRM1 (0.42) | ACHENR1H4CHRM1CHRM3CHRM5 | |
| SCHEMBL3819363 | 0.79 | ATM (0.39) | LMNAACHEOPRM1NR1H4CHRM1 | |
| SCHEMBL4735205 | 0.78 | ALDH1A1 (0.41) | LMNAMAPTACHEOPRM1CHRM1 | |
| SCHEMBL4737099 | 0.76 | ALDH1A1 (0.43) | LMNAMAPTNPSR1KDM4EHTT | |
| SCHEMBL4739034 | 0.76 | ACHE (0.40) | ACHEOPRM1NR1H4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |