Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 6/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734946 | 0.82 | LMNA (0.58) | ALDH1A1LMNAMEN1POLBKMT2A | |
| SCHEMBL4735333 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1POLBKMT2A | |
| SCHEMBL4738981 | 0.78 | LMNA (0.41) | LMNA | |
| SCHEMBL3821794 | 0.78 | OPRM1 (0.39) | ALDH1A1LMNAMAOAKDM4EHTT | |
| SCHEMBL3059109 | 0.77 | ACHE (0.39) | LMNAMEN1KMT2ACYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL3064216 | 0.77 | ACHE (0.39) | LMNAMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL4733711 | 0.76 | LMNA (0.39) | ALDH1A1LMNAKDM4EHTTMAPT | |
| SCHEMBL3064159 | 0.76 | CHRM1 (0.42) | MEN1KMT2A | |
| SCHEMBL3819363 | 0.76 | ATM (0.39) | LMNA | |
| SCHEMBL4736548 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |