Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | NPY2R | P49146 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184199 | 0.81 | MAPK14 (0.44) | CNR1CNR2PDK1CYP3A4HDAC1 | |
| SCHEMBL8190064 | 0.79 | CYP3A4 (0.42) | CNR1CNR2PDK1CYP3A4GPBAR1 | |
| SCHEMBL4738668 | 0.77 | CNR2 (0.40) | CNR1CNR2PDK1CYP3A4GPBAR1 | |
| SCHEMBL4733577 | 0.77 | TLR7 (0.40) | CNR1CNR2CYP3A4GPBAR1 | |
| SCHEMBL4738921 | 0.76 | TRPM8 (0.43) | OPRM1NPY2RPDK1HDAC3HDAC1 | |
| SCHEMBL3818747 | 0.76 | CNR2 (0.47) | CNR1CNR2CYP3A4RAB9A | |
| SCHEMBL4735258 | 0.76 | ALDH1A1 (0.52) | CNR2CYP3A4RAB9A | |
| SCHEMBL4739106 | 0.75 | NPC1 (0.41) | CNR1CNR2PDK1CYP3A4RAB9A | |
| SCHEMBL3824123 | 0.74 | CNR1 (0.41) | CNR1CNR2CYP3A4GPBAR1 | |
| SCHEMBL4733672 | 0.72 | ALDH1A1 (0.44) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |