Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735594 | 0.91 | OPRM1 (0.48) | OPRM1HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL4739792 | 0.89 | LMNA (0.49) | OPRM1LMNAKDM4EALDH1A1TSHR | |
| SCHEMBL4735586 | 0.88 | LMNA (0.53) | OPRM1LMNAKDM4EALDH1A1TSHR | |
| SCHEMBL4738710 | 0.88 | LMNA (0.49) | OPRM1HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL4733936 | 0.87 | OPRM1 (0.49) | OPRM1HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL4734088 | 0.87 | LMNA (0.53) | OPRM1OPRK1LMNAKDM4EALDH1A1 | |
| SCHEMBL4735444 | 0.86 | LMNA (0.52) | OPRM1OPRK1LMNAKDM4EALDH1A1 | |
| SCHEMBL4737945 | 0.86 | OPRM1 (0.44) | OPRM1HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL4737984 | 0.86 | ALDH1A1 (0.53) | DRD4DRD3LMNAKDM4EALDH1A1 | |
| SCHEMBL4740309 | 0.85 | LMNA (0.46) | OPRM1LMNAKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |