Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739792 | 0.89 | LMNA (0.49) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4735594 | 0.87 | OPRM1 (0.48) | LMNAALDH1A1KDM4ETSHROPRM1 | |
| SCHEMBL4738710 | 0.87 | LMNA (0.49) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4734088 | 0.86 | LMNA (0.53) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4735586 | 0.86 | LMNA (0.53) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4735444 | 0.86 | LMNA (0.52) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4738686 | 0.85 | OPRM1 (0.55) | LMNAALDH1A1KDM4ETSHROPRM1 | |
| SCHEMBL4737984 | 0.85 | ALDH1A1 (0.53) | LMNAALDH1A1NPSR1KDM4ETSHR | |
| SCHEMBL4735549 | 0.84 | MEN1 (0.43) | MEN1KMT2AATMALDH1A1NPSR1 | |
| SCHEMBL4736577 | 0.84 | TSHR (0.49) | LMNAMEN1KMT2AATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |