Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735594 | 0.91 | OPRM1 (0.48) | LMNAALDH1A1TSHRKDM4EOPRM1 | |
| SCHEMBL4738710 | 0.91 | LMNA (0.49) | LMNAALDH1A1TSHRKDM4EOPRM1 | |
| SCHEMBL4734088 | 0.91 | LMNA (0.53) | LMNAALDH1A1TSHRKDM4EOPRM1 | |
| SCHEMBL4735586 | 0.90 | LMNA (0.53) | LMNAALDH1A1TSHRKDM4EOPRM1 | |
| SCHEMBL4735444 | 0.90 | LMNA (0.52) | LMNAALDH1A1TSHRKDM4EOPRM1 | |
| SCHEMBL4738686 | 0.89 | OPRM1 (0.55) | LMNAALDH1A1TSHRKDM4EOPRM1 | |
| SCHEMBL4737984 | 0.89 | ALDH1A1 (0.53) | LMNAALDH1A1TSHRKDM4ETP53 | |
| SCHEMBL4740309 | 0.89 | LMNA (0.46) | LMNAALDH1A1TSHRKDM4EOPRM1 | |
| SCHEMBL4736215 | 0.85 | LMNA (0.48) | LMNAALDH1A1TSHRKDM4EOPRM1 | |
| SCHEMBL4785360 | 0.85 | LMNA (0.46) | LMNAALDH1A1TSHRKDM4EOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |