Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4803555 | 0.91 | ME2 (0.39) | ALDH1A1SMN1; SMN2DRD2DRD3DRD4 | |
| SCHEMBL4734210 | 0.88 | HTR1A (0.47) | ALDH1A1DRD2DRD3DRD4HTR1A | |
| SCHEMBL4734880 | 0.87 | MEN1 (0.37) | ALDH1A1SMN1; SMN2CYP1A2USP2DRD2 | |
| SCHEMBL4737954 | 0.84 | KDM4E (0.45) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9DRD2 | |
| SCHEMBL3065998 | 0.82 | KDM4E (0.46) | ALDH1A1SMN1; SMN2CYP1A2HSD17B10CYP2C9 | |
| SCHEMBL3826319 | 0.82 | DRD4 (0.47) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9DRD2 | |
| SCHEMBL4738710 | 0.82 | LMNA (0.49) | ALDH1A1SMN1; SMN2CYP1A2HSD17B10CYP2C9 | |
| SCHEMBL4737305 | 0.82 | DRD4 (0.45) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9DRD2 | |
| SCHEMBL4739086 | 0.82 | TSHR (0.52) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9DRD2 | |
| SCHEMBL4737347 | 0.80 | DRD4 (0.43) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |