Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 7/20 | 0.61 |
| ▸ | SLC5A2 | P31639 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | CBS | P35520 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457057 | 0.79 | SLC5A1 (0.65) | SLC5A1SLC5A2MAPTGAACBS | |
| SCHEMBL31237673 | 0.79 | SLC5A1 (0.49) | SLC5A1SLC5A2MAPTGAACBS | |
| SCHEMBL455029 | 0.77 | SLC5A1 (1.00) | SLC5A1SLC5A2MAPTGAACBS | |
| SCHEMBL31040543 | 0.76 | CBS (0.75) | SLC5A1SLC5A2MAPTGAACBS | |
| SCHEMBL11152281 | 0.75 | CYP3A4 (0.51) | MAPTGAACYP3A4MEN1ALDH1A1 | |
| SCHEMBL31230884 | 0.75 | CTSL (0.69) | SLC5A1SLC5A2MAPTGAACBS | |
| SCHEMBL31040538 | 0.75 | PLA2G2A (0.64) | MAPTCYP3A4MEN1ALDH1A1LMNA | |
| SCHEMBL31040537 | 0.74 | FFAR1 (0.50) | MAPTCYP3A4MEN1KMT2AALOX5 | |
| SCHEMBL24842064 | 0.73 | ACHE (0.75) | SLC5A1SLC5A2MAPTGAACBS | |
| SCHEMBL30460437 | 0.72 | CYP3A4 (0.70) | MAPTCYP3A4KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858641-B1 | IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION | BASF CORP (US) | 2017-09-06 | — | — | EP | claimed |
| EP-2888012-B1 | ORAL CARE | UNIV PRETORIA (ZA) | 2020-06-17 | — | — | EP | disclosed |
| EP-2888012-A2 | ORAL CARE | University of Pretoria (ZA) | 2015-07-01 | — | — | EP | disclosed |
| US-20150174059-A1 | ORAL CARE | UNIVERSITY OF PRETORIA (ZA) | 2015-06-25 | — | — | US | disclosed |
| WO-2014033625-A2 | ORAL CARE | UNIVERSITY OF PRETORIA (ZA) | 2014-03-06 | — | — | WO | disclosed |
| WO-2008100977-A2 | CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS | N.V. ORGANON (NL) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174059-A1 | ORAL CARE | NOP2, POLR1C, DPM1 | SLC5A1 4623/4885SLC5A2 4424/4885MAPT 2090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.