Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749902 | 0.91 | GPR183 (0.53) | L3MBTL1ALDH1A1ACHE | |
| SCHEMBL4747050 | 0.89 | KDM4E (0.52) | L3MBTL1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL4746545 | 0.88 | ME2 (0.44) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL4809360 | 0.87 | L3MBTL1 (0.53) | L3MBTL1KDM4EKMT2AALDH1A1TDP1 | |
| SCHEMBL4749877 | 0.86 | KDM4E (0.46) | KDM4EKMT2AALDH1A1TDP1MEN1 | |
| SCHEMBL4750248 | 0.84 | LMNA (0.47) | L3MBTL1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4749965 | 0.75 | KDM4E (0.43) | KDM4EKMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL4817000 | 0.75 | ME2 (0.44) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL4749968 | 0.74 | KDM4E (0.48) | KDM4EKMT2AALDH1A1TDP1MEN1 | |
| SCHEMBL4749356 | 0.71 | KDM4E (0.42) | KDM4EKMT2AALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | disclosed |