Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749923 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL4749360 | 0.90 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL4746294 | 0.90 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL4787866 | 0.89 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4749356 | 0.88 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL4747065 | 0.85 | LIPE (0.40) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL4074550 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL4746748 | 0.80 | L3MBTL1 (0.44) | KDM4EALDH1A1HSD17B10DRD2MAPK1 | |
| SCHEMBL4787804 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL4746545 | 0.78 | ME2 (0.44) | KDM4EALDH1A1HPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |