Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 11/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747137 | 0.91 | L3MBTL1 (0.53) | ACHEALDH1A1L3MBTL1 | |
| SCHEMBL4746545 | 0.91 | ME2 (0.44) | GPR183MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4749877 | 0.89 | KDM4E (0.46) | GPR183ACHEMAPTALDH1A1NPC1 | |
| SCHEMBL4747050 | 0.87 | KDM4E (0.52) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL4749260 | 0.84 | CCNC (0.38) | ACHEMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4750248 | 0.83 | LMNA (0.47) | TP53ALDH1A1L3MBTL1 | |
| SCHEMBL4809360 | 0.78 | L3MBTL1 (0.53) | ACHEMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4817000 | 0.77 | ME2 (0.44) | GPR183MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4749968 | 0.76 | KDM4E (0.48) | GPR183ACHEMAPTALDH1A1NPC1 | |
| SCHEMBL4749965 | 0.76 | KDM4E (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | disclosed |