Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749923 | 0.89 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL4746294 | 0.88 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL4749965 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL4749360 | 0.88 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL4787866 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4747065 | 0.81 | LIPE (0.40) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL4746748 | 0.76 | L3MBTL1 (0.44) | KDM4EALDH1A1HSD17B10MAPK1TSHR | |
| SCHEMBL4787804 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL4749260 | 0.76 | CCNC (0.38) | KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL4069470 | 0.74 | MAOA (0.37) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |