Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.35 |
| ▸ | TK2 | O00142 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30841853 | 0.88 | ALDH1A1 (0.41) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL339966 | 0.88 | ALDH1A1 (0.41) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL4749295 | 0.84 | PYGM (0.39) | TK1TK2ALDH1A1LMNAALB | |
| SCHEMBL28377042 | 0.78 | SLC28A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL2633815 | 0.72 | LMNA (0.41) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9545108 | 0.72 | TK2 (0.40) | TK1TK2LMNAADRA1A | |
| SCHEMBL28765909 | 0.72 | LMNA (0.42) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL2012504 | 0.72 | ALDH1A1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL19387606 | 0.71 | TK1 (0.44) | TK1TK2LMNAADRA1ABLM | |
| SCHEMBL8412869 | 0.71 | ALDH1A1 (0.40) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118879-A2 | ANTIVIRAL COMPOSITIONS COMPRISING 2 COMPOUNDS | ARDEA BIOSCIENCES, INC. (US) | 2008-10-02 | — | — | WO | disclosed |