Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5624141 | 0.83 | MEN1 (0.39) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL9474853 | 0.76 | PTGER1 (0.42) | MEN1KMT2ASMN1; SMN2LMNAXBP1 | |
| SCHEMBL4748576 | 0.74 | KMT2A (0.44) | KMT2ASMN1; SMN2HSP90AA1ALDH1A1LMNA | |
| SCHEMBL9139069 | 0.71 | CA2 (0.38) | ALDH1A1NPSR1CA2 | |
| SCHEMBL7085230 | 0.71 | LMNA (0.41) | KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10767180 | 0.68 | CASP1 (0.42) | MEN1KMT2ASMN1; SMN2BCAT2PTGS2 | |
| SCHEMBL21794264 | 0.67 | TSHR (0.46) | HNF4AKMT2ASMN1; SMN2BCAT2PTGS2 | |
| SCHEMBL15879480 | 0.65 | ALDH1A1 (0.56) | ALDH1A1LMNACA12CA1CA2 | |
| Bicarbonate SCHEMBL10531683 | 0.65 | BCAT2 (0.58) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 | |
| Bicarbonate SCHEMBL10341263 | 0.65 | BCAT2 (0.58) | HNF4AMEN1KMT2ASMN1; SMN2BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | disclosed |
| US-5384328-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| US-5336690-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0592439-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1994-04-20 | — | — | EP | disclosed |
| WO-1992008693-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |