Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474853 | 0.89 | PTGER1 (0.42) | MEN1KMT2ASMN1; SMN2ESR1 | |
| SCHEMBL7086352 | 0.83 | HNF4A (0.40) | MEN1KMT2ASMN1; SMN2BCAT2CHRNB2 | |
| SCHEMBL9175530 | 0.75 | C5AR1 (0.50) | KMT2ASMN1; SMN2PTGS2STAT3ESR1 | |
| SCHEMBL23374991 | 0.74 | KMT2A (0.46) | MEN1KMT2ASMN1; SMN2BCAT2CHRNB2 | |
| SCHEMBL4748576 | 0.74 | KMT2A (0.44) | KMT2ASMN1; SMN2ALDH1A1ESR1HPGD | |
| SCHEMBL9452056 | 0.73 | ALDH1A1 (0.36) | ALDH1A1CA2 | |
| SCHEMBL27637324 | 0.71 | BCAT2 (0.47) | MEN1KMT2ASMN1; SMN2BCAT2CHRNB2 | |
| SCHEMBL5883327 | 0.71 | TACR1 (0.54) | MEN1KMT2ASMN1; SMN2BCAT2TACR1 | |
| SCHEMBL7200742 | 0.69 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2BCAT2TACR1 | |
| SCHEMBL10785562 | 0.69 | NPSR1 (0.48) | MEN1KMT2ASMN1; SMN2BCAT2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244845-B2 | Process for preparing cyclic N-substituted alpha-imino carboxylic acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-07-17 | — | — | US | claimed |
| US-20050131231-A1 | Process for preparing cyclic N-substituted alpha-imino carboxlic acids | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-06-16 | — | — | US | claimed |
| US-7244845-B2 | Process for preparing cyclic N-substituted alpha-imino carboxylic acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20050131231-A1 | Process for preparing cyclic N-substituted alpha-imino carboxlic acids | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131231-A1 | Process for preparing cyclic N-substituted alpha-imino carboxlic acids | MMP1, MMP2, MMP9 | MEN1 1522/4885KMT2A 3325/4885SMN1; SMN2 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.