Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | SELL | P14151 | 2/20 | 0.34 |
| ▸ | SELP | P16109 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12164010 | 0.86 | PTGS2 (0.37) | PTGDR2PTGS2PPARGFFAR1PPARD | |
| SCHEMBL474492 | 0.86 | PTGS2 (0.37) | PTGDR2PTGS2PPARGFFAR1PPARD | |
| SCHEMBL474975 | 0.82 | ALDH1A1 (0.35) | PTGDR2PTGS2CMA1ALDH1A1GLA | |
| SCHEMBL474936 | 0.82 | ADORA2A (0.42) | PTGDR2PPARGPPARDPPARASMN1; SMN2 | |
| SCHEMBL474633 | 0.79 | ALDH1A1 (0.41) | CMA1ALDH1A1GLASMN1; SMN2MAPK14 | |
| SCHEMBL474933 | 0.78 | PPARG (0.39) | PTGDR2PPARGPPARDALDH1A1SMN1; SMN2 | |
| SCHEMBL474606 | 0.78 | RXRA (0.40) | PTGS2PPARGPPARDALDH1A1 | |
| SCHEMBL12164001 | 0.78 | RXRA (0.40) | PTGS2PPARGPPARDALDH1A1 | |
| SCHEMBL474521 | 0.77 | TP53 (0.39) | CMA1ALDH1A1GLASMN1; SMN2MAPK14 | |
| SCHEMBL474454 | 0.74 | SMN1; SMN2 (0.39) | PTGDR2PPARGFFAR1PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411365-A1 | 2,3-DIARYL- OR HETEROARYL-SUBSTITUTED 1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2012-02-01 | — | — | EP | disclosed |