Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747050 | 0.89 | KDM4E (0.52) | LMNAKDM4ENPC1RAB9AMEN1 | |
| SCHEMBL4746545 | 0.88 | ME2 (0.44) | LMNACCR4KDM4ENPC1RAB9A | |
| SCHEMBL4749877 | 0.84 | KDM4E (0.46) | LMNAKDM4ENPC1RAB9AMEN1 | |
| SCHEMBL4749902 | 0.84 | GPR183 (0.53) | NPC1RAB9AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4747137 | 0.83 | L3MBTL1 (0.53) | LMNAKDM4EMEN1KMT2AHPGD | |
| SCHEMBL4750248 | 0.82 | LMNA (0.47) | LMNAKDM4EHPGDALDH1A1POLB | |
| SCHEMBL4749965 | 0.78 | KDM4E (0.43) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL4749923 | 0.76 | KDM4E (0.44) | KDM4ENPSR1HPGDALDH1A1POLB | |
| SCHEMBL4749356 | 0.76 | KDM4E (0.42) | KDM4EKMT2AHPGDALDH1A1 | |
| SCHEMBL4749360 | 0.75 | ALDH1A1 (0.55) | LMNAKDM4EMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | disclosed |