Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 2/20 | 0.34 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851695 | 0.77 | NPSR1 (0.49) | IDO1LMNAPOLB | |
| SCHEMBL12494028 | 0.76 | TRPV1 (0.34) | — | |
| SCHEMBL28587432 | 0.73 | CACNA1G (0.44) | TDP1LMNAPOLB | |
| SCHEMBL3017280 | 0.72 | L3MBTL1 (0.54) | KDM4ATDP1CA12CA1CA2 | |
| SCHEMBL16935831 | 0.71 | MALT1 (0.50) | LATS1TDP1CA12CA1CA2 | |
| SCHEMBL5663146 | 0.71 | DGAT1 (0.49) | TDP1MALT1NAMPTLMNAPOLB | |
| SCHEMBL3699220 | 0.71 | SHBG (0.49) | KDM4ATDP1LMNA | |
| SCHEMBL398349 | 0.70 | EPHX2 (0.42) | KDM4ATDP1CA12CA1CA2 | |
| SCHEMBL17570719 | 0.70 | ALDH1A1 (0.39) | KDM4ATDP1CA12CA1CA2 | |
| SCHEMBL11961188 | 0.70 | CA2 (0.55) | TDP1CA1CA2IDO1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143729-A2 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008106225-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |