Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.38 |
| ▸ | ILK | Q13418 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788883 | 0.84 | TSHR (0.39) | HTR2AALDH1A1CA12CA1CA2 | |
| SCHEMBL10805819 | 0.82 | LMNA (0.36) | AKT1PDPK1PHLPP1ILKHTR2A | |
| SCHEMBL23667871 | 0.75 | SELL (0.37) | AKT1HTR2AALDH1A1LMNAMAPT | |
| SCHEMBL4750506 | 0.74 | AKT1 (0.36) | AKT1PDPK1PHLPP1ILKHTR2A | |
| SCHEMBL4752969 | 0.74 | PKM (0.46) | ALDH1A1MAPT | |
| SCHEMBL4750485 | 0.73 | HTR2A (0.51) | AKT1HTR2AALDH1A1LMNA | |
| SCHEMBL23667872 | 0.73 | HTR2A (0.38) | AKT1HTR2AALDH1A1LMNAMAPT | |
| SCHEMBL4754019 | 0.73 | ALOX15 (0.37) | AKT1HTR2AALDH1A1LMNAMAPT | |
| SCHEMBL30079686 | 0.73 | ALOX15 (0.37) | AKT1HTR2AALDH1A1LMNAMAPT | |
| SCHEMBL10689616 | 0.73 | CA2 (0.45) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |