Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 10/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756695 | 0.86 | HSD11B1 (0.39) | HSD11B1KITPSDUSP30KDM4E | |
| SCHEMBL4755140 | 0.82 | HSD11B1 (0.38) | HSD11B1KITPSDUSP30FASN | |
| SCHEMBL4753279 | 0.80 | FASN (0.32) | HSD11B1KITPSDUSP30KDM4E | |
| SCHEMBL13746898 | 0.78 | HSD11B1 (0.39) | HSD11B1KITPSDKDM4EALDH1A1 | |
| SCHEMBL4756614 | 0.71 | KDM4E (0.33) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13747135 | 0.69 | HSD11B1 (0.35) | HSD11B1KITKDM4EALDH1A1MAPT | |
| SCHEMBL13985228 | 0.69 | CRHR1 (0.35) | HSD11B1 | |
| SCHEMBL13746941 | 0.67 | EIF4E (0.36) | PSD | |
| SCHEMBL4753233 | 0.67 | PDE9A (0.37) | HSD11B1KITPSDUSP30KDM4E | |
| SCHEMBL13746668 | 0.66 | TYMS (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |