Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 5/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | UBE2N | P61088 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755201 | 0.80 | HSD11B1 (0.38) | FASNUSP30KDM4EALDH1A1HPGD | |
| SCHEMBL4755648 | 0.72 | PIK3CA (0.35) | PDE9A | |
| SCHEMBL4753233 | 0.72 | PDE9A (0.37) | USP30PDE9AKDM4EALDH1A1HPGD | |
| SCHEMBL4753289 | 0.68 | MAT2A (0.34) | — | |
| SCHEMBL4756695 | 0.66 | HSD11B1 (0.39) | FASNUSP30PDE9AKDM4EALDH1A1 | |
| SCHEMBL4755691 | 0.65 | USP14 (0.36) | KDM4EALDH1A1MAPT | |
| SCHEMBL4755140 | 0.62 | HSD11B1 (0.38) | FASNUSP30PSDKITHSD11B1 | |
| SCHEMBL13985503 | 0.61 | USP14 (0.35) | KDM4EALDH1A1MAPT | |
| SCHEMBL13746898 | 0.60 | HSD11B1 (0.39) | FASNPDE9AKDM4EALDH1A1HPGD | |
| SCHEMBL13747135 | 0.59 | HSD11B1 (0.35) | FASNPDE9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |