Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | FASN | P49327 | 6/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 3/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756695 | 0.84 | HSD11B1 (0.39) | HSD11B1FASNPSDKITUSP30 | |
| SCHEMBL4755201 | 0.82 | HSD11B1 (0.38) | HSD11B1FASNPSDKITUSP30 | |
| SCHEMBL13746898 | 0.76 | HSD11B1 (0.39) | HSD11B1FASNPSDKIT | |
| SCHEMBL4756614 | 0.69 | KDM4E (0.33) | — | |
| SCHEMBL13747135 | 0.67 | HSD11B1 (0.35) | HSD11B1FASNKIT | |
| SCHEMBL13985227 | 0.66 | NOTUM (0.39) | HSD11B1 | |
| SCHEMBL4753233 | 0.65 | PDE9A (0.37) | HSD11B1PSDKITUSP30 | |
| SCHEMBL4755759 | 0.63 | LMNA (0.37) | — | |
| SCHEMBL4022798 | 0.63 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL4753279 | 0.62 | FASN (0.32) | HSD11B1FASNPSDKITUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |