Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 3/20 | 0.36 |
| ▸ | FASN | P49327 | 7/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755201 | 0.86 | HSD11B1 (0.38) | HSD11B1KITFASNPSDUSP30 | |
| SCHEMBL4755140 | 0.84 | HSD11B1 (0.38) | HSD11B1KITFASNPSDUSP30 | |
| SCHEMBL4756614 | 0.84 | KDM4E (0.33) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL13746898 | 0.83 | HSD11B1 (0.39) | HSD11B1KITFASNPSDPDE9A | |
| SCHEMBL4753233 | 0.81 | PDE9A (0.37) | HSD11B1KITPSDUSP30PDE9A | |
| SCHEMBL4753259 | 0.74 | PIK3CA (0.35) | PDE9A | |
| SCHEMBL13747135 | 0.73 | HSD11B1 (0.35) | HSD11B1KITFASNPDE9AKDM4E | |
| SCHEMBL13746012 | 0.69 | PIK3CA (0.36) | PDE9A | |
| SCHEMBL4022798 | 0.68 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL13747129 | 0.68 | TYMS (0.38) | PSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |