Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4814956 | 0.90 | ALDH1A1 (0.32) | DGAT1MYCNR4A1KMT2AALDH1A1 | |
| SCHEMBL4755368 | 0.82 | HCAR2 (0.36) | — | |
| SCHEMBL4755352 | 0.79 | GAA (0.34) | MYCNR4A1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4822378 | 0.78 | LMNA (0.34) | LMNA | |
| SCHEMBL4756122 | 0.77 | GAA (0.30) | — | |
| SCHEMBL4758585 | 0.68 | FPR2 (0.37) | DGAT1MYCNR4A1MAP2K1FPR2 | |
| SCHEMBL5458967 | 0.63 | MAPT (0.39) | FPR2KMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6519772 | 0.62 | DGAT1 (0.41) | DGAT1FPR2KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4757298 | 0.61 | ALDH1A1 (0.37) | MYCNR4A1MAP2K1FPR2KMT2A | |
| SCHEMBL29581091 | 0.61 | DGAT1 (0.43) | DGAT1KMT2AALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006070-A2 | COMPOUNDS AND COMBINATIONS THEREOF FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF USE THEREOF | ROSKAMP RESEARCH LLC (US) | 2008-01-10 | — | — | WO | disclosed |