Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269133 | 0.92 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL158270 | 0.84 | RAB9A (0.68) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16594362 | 0.84 | TSHR (0.56) | SMN1; SMN2LMNAMAPTRAB9AMAOA | |
| SCHEMBL8392921 | 0.84 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL6536372 | 0.84 | CHRNA7 (0.46) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL1662622 | 0.83 | MAOA (0.75) | ALDH1A1HPGDRAB9AMAOAMAOB | |
| SCHEMBL865349 | 0.83 | RAB9A (0.71) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL5677947 | 0.83 | LMNA (0.62) | SMN1; SMN2LMNAMAPTRAB9AMAOA | |
| SCHEMBL903883 | 0.82 | TSHR (0.58) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL8371513 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |