Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | PAM | P19021 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1507284 | 1.00 | SIGMAR1 (0.46) | SIGMAR1IDO1PAMHTR2AMAOB | |
| SCHEMBL1507325 | 0.94 | SIGMAR1 (0.44) | SIGMAR1IDO1PAMHTR2AMAOB | |
| SCHEMBL7026121 | 0.92 | SIGMAR1 (0.43) | SIGMAR1IDO1PAMHTR2AMAOB | |
| SCHEMBL7031324 | 0.92 | SIGMAR1 (0.43) | SIGMAR1IDO1PAMHTR2AMAOB | |
| SCHEMBL7613933 | 0.92 | SIGMAR1 (0.43) | SIGMAR1IDO1PAMHTR2AMAOB | |
| SCHEMBL7613927 | 0.92 | SIGMAR1 (0.43) | SIGMAR1IDO1PAMHTR2AMAOB | |
| SCHEMBL3320625 | 0.92 | SIGMAR1 (0.43) | SIGMAR1IDO1PAMHTR2AMAOB | |
| SCHEMBL11503226 | 0.92 | SIGMAR1 (0.43) | SIGMAR1IDO1PAMHTR2AMAOB | |
| SCHEMBL3031009 | 0.92 | SIGMAR1 (0.43) | SIGMAR1IDO1PAMHTR2AMAOB | |
| SCHEMBL11503225 | 0.92 | SIGMAR1 (0.43) | SIGMAR1IDO1PAMHTR2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-07-14 | — | — | US | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
| EP-2794617-B1 | PROCESS FOR THE PREPARATION OF BENZODITHIOPHENE COMPOUNDS | ENI SPA (IT) | 2016-03-09 | — | — | EP | disclosed |
| EP-2738175-B1 | Process for the preparation of benzodithiophene compounds | ENI SPA (IT) | 2015-10-14 | — | — | EP | disclosed |
| US-8981118-B2 | Process for the preparation of benzodithiophene compounds | ENI S.P.A. (IT) | 2015-03-17 | — | — | US | disclosed |
| US-20140364628-A1 | PROCESS FOR THE PREPARATION OF BENZODITHIOPHENE COMPOUNDS | ENI S.P.A. (IT) | 2014-12-11 | — | — | US | disclosed |
| US-8853425-B2 | Process for the preparation of benzodithiophene compounds | ENI S.P.A. (IT) | 2014-10-07 | — | — | US | disclosed |
| EP-2769981-A1 | Improved process for the preparation of benzodithiophene compounds | ENI S.p.A. (IT) | 2014-08-27 | — | — | EP | disclosed |
| US-20140235874-A1 | PROCESS FOR THE PREPARATION OF BENZODITHIOPHENE COMPOUNDS | ENI S.P.A (IT) | 2014-08-21 | — | — | US | disclosed |
| US-20140155631-A1 | PROCESS FOR THE PREPARATION OF BENZODITHIOPHENE COMPOUNDS | ENI S.P.A. (IT) | 2014-06-05 | — | — | US | disclosed |
| EP-1400513-B1 | UNSYMMETRICAL CYCLIC DIAMINE COMPOUND | KOWA CO (JP) | 2008-01-09 | — | — | EP | disclosed |
| EP-1400513-B1 | UNSYMMETRICAL CYCLIC DIAMINE COMPOUND | KOWA CO (JP) | 2008-01-09 | — | — | EP | disclosed |
| CN-1520402-A | Unsymmetrical cyclic diamine compound | ������������ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| EP-1400513-A1 | UNSYMMETRICAL CYCLIC DIAMINE COMPOUND | Kowa Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6552188-B2 | Inhibit cell adhesion and cell infiltration; useful treating asthma, allergies, rheumatic diseases, arteriosclerosis, and inflammation; 2-(3,4,5-trimethoxyphenyl),4-((4-substituted piperazin-1-yl)methyl)pyridine compounds | KOWA CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-20030022887-A1 | Unsymmetrical cyclic diamine compound | KOWA CO., LTD. (JP) | 2003-01-30 | — | — | US | disclosed |
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |
| EP-0226636-B1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0226636-A1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1987-07-01 | — | — | EP | disclosed |
| WO-1987000521-A2 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1987-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155631-A1 | PROCESS FOR THE PREPARATION OF BENZODITHIOPHENE COMPOUNDS | DDC, DDT, AOC1 | SIGMAR1 2372/4885IDO1 1616/4885PAM 2364/4885 |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | SIGMAR1 3642/4885IDO1 374/4885PAM 949/4885 |
| US-20030022887-A1 | Unsymmetrical cyclic diamine compound | H1-0, DDAH1, AOC1 | SIGMAR1 152/4885IDO1 2474/4885PAM 519/4885 |
| US-20140364628-A1 | PROCESS FOR THE PREPARATION OF BENZODITHIOPHENE COMPOUNDS | DDC, DLST, HLCS | SIGMAR1 3991/4885IDO1 2908/4885PAM 1218/4885 |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | PPOX, CYBA, CYBB | SIGMAR1 3642/4885IDO1 374/4885PAM 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.