SCHEMBL4765265

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4770531	0.89	PTGS2 (0.43)	CA2SMN1; SMN2PTGS2
	SCHEMBL4773979	0.85	CA2 (0.56)	CA2SMN1; SMN2TSHRCA1CA7
	SCHEMBL4763911	0.84	ALDH1A1 (0.43)	GAACA2SMN1; SMN2TSHRCA1
	SCHEMBL1983658	0.83	TSHR (0.32)	TSHRLMNACYP2C9
	SCHEMBL4774829	0.82	SMN1; SMN2 (0.47)	GAACA2SMN1; SMN2TSHRCA1
	SCHEMBL3846515	0.82	LMNA (0.44)	GAASMN1; SMN2PKMMAPK1ALDH1A1
	SCHEMBL4769186	0.81	LMNA (0.56)	GAASMN1; SMN2TSHRALDH1A1LMNA
	SCHEMBL4768844	0.81	ALDH1A1 (0.54)	CA2SMN1; SMN2TSHRCA1CA9
	SCHEMBL4763544	0.80	CA12 (0.57)	GAACA2SMN1; SMN2TSHRCA1
	SCHEMBL4770234	0.79	TDP1 (0.41)	GAACA2SMN1; SMN2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.