Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29488522 | 1.00 | MAPT (0.44) | MAPTALDH1A1POLBL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL29378499 | 1.00 | MAPT (0.44) | MAPTALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL821151 | 0.99 | MAPT (0.45) | MAPTALDH1A1POLBL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL15380794 | 0.98 | MAPT (0.44) | MAPTALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL12224171 | 0.89 | MAPT (0.46) | MAPTALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL3860604 | 0.86 | HCRTR1 (0.44) | MAPTALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL22809830 | 0.86 | ALOX15 (0.45) | MAPTALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL29566503 | 0.86 | HCRTR1 (0.44) | MAPTALDH1A1POLBL3MBTL1LMNA | |
| Trimethylammonium SCHEMBL3407456 | 0.85 | MAPT (0.43) | MAPTALDH1A1POLBL3MBTL1LMNA | |
| Chloromethane SCHEMBL1132739 | 0.84 | HCRTR1 (0.42) | MAPTALDH1A1POLBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836984-B2 | Method for stabilizing both lipase and protease in liquid enzymatic laundry detergent | JIANGNAN UNIVERSITY (CN) | 2020-11-17 | — | — | US | claimed |
| CN-107119036-B | Method for stabilizing protease in laundry detergent | 江南大学 | 2020-07-03 | — | — | CN | claimed |
| EP-2582745-B1 | COATING FORMULATION FOR PREPARING A HYDROPHILIC COATING | DSM IP ASSETS BV (NL) | 2019-01-09 | — | — | EP | claimed |
| US-20180320112-A1 | METHOD FOR STABILIZING BOTH LIPASE AND PROTEASE IN LIQUID ENZYMATIC LAUNDRY DETERGENT | JIANGNAN UNIVERSITY (CN) | 2018-11-08 | — | — | US | claimed |
| EP-2225388-B1 | COMPOSITIONS FOR FORMING IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING | ABBOTT POINT OF CARE INC (US) | 2016-03-30 | — | — | EP | claimed |
| US-8268604-B2 | Compositions for forming immobilized biological layers for sensing | ABBOTT POINT OF CARE INC. (US) | 2012-09-18 | — | — | US | claimed |
| JP-2011508221-A | — | — | 2011-03-10 | — | — | JP | claimed |
| US-20100255120-A1 | COMPOSITIONS FOR FORMING IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING | ABBOTT POINT OF CARE INC. | 2010-10-07 | — | — | US | claimed |
| EP-2225388-A1 | COMPOSITIONS FOR FORMING IMMOBIIZED BIOLOGICAL LAYERS FOR SENSING | Abbott Point Of Care, Inc. (US) | 2010-09-08 | — | — | EP | claimed |
| US-20100215635-A1 | SMALL MOLECULES TO INDUCE WEIGHT LOSS OR TO REDUCE WEIGHT GAIN | KISS ZOLTAN | 2010-08-26 | — | — | US | claimed |
| EP-1610831-B1 | COLOR-STABLE SUPERABSORBENT POLYMER COMPOSITION | BASF AG (DE) | 2006-08-30 | — | — | EP | claimed |
| US-20060166141-A1 | Photoresists; photomasks | PRESSTEK, INC. (US) | 2006-07-27 | — | — | US | claimed |
| WO-2006044267-A2 | INKJET-IMAGEABLE LITHOGRAPHIC PRINTING MEMBERS AND METHODS OF PREPARING AND IMAGING THEM | PRESSTEK, INC. (US) | 2006-04-27 | — | — | WO | claimed |
| US-20060089611-A1 | Color-stable superabsorbent polymer composition | BASF AKTIENGESELLSCHAFT (DE) | 2006-04-27 | — | — | US | claimed |
| EP-1611165-A1 | COLOR-STABLE SUPERABSORBENT POLYMER COMPOSITION | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-04 | — | — | EP | claimed |
| EP-1610831-A1 | COLOR-STABLE SUPERABSORBENT POLYMER COMPOSITION | BASF Aktiengesellschaft (DE) | 2006-01-04 | — | — | EP | claimed |
| WO-2004085496-A1 | COLOR-STABLE SUPERABSORBENT POLYMER COMPOSITION | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-07 | — | — | WO | claimed |
| WO-2004084962-A1 | COLOR-STABLE SUPERABSORBENT POLYMER COMPOSITION | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-07 | — | — | WO | claimed |
| US-5824716-A | ULTRAVIOLET RADIATION CURABLE AQUEOUS LATEX OF PHOTOINITIATOR AND DICYCLOPENTENYLOXYETHYL METHACRYLATE COPOLYMER; COALESCING, CROSSLINKING; PAINTS, LACQUERS | ELF ATOCHEM S.A. (FR) | 1998-10-20 | — | — | US | claimed |
| EP-0740691-B1 | PHOTOCURABLE FILM-FORMING ACRYLIC LATICES | ATOCHEM ELF SA (FR) | 1998-07-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100215635-A1 | SMALL MOLECULES TO INDUCE WEIGHT LOSS OR TO REDUCE WEIGHT GAIN | GPR119, FABP4, PNLIP | MAPT 3901/4885ALDH1A1 1372/4885POLB 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.