Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloromethane SCHEMBL1132739 | 0.91 | HCRTR1 (0.42) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL3860604 | 0.91 | HCRTR1 (0.44) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL29566503 | 0.91 | HCRTR1 (0.44) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL12224171 | 0.87 | MAPT (0.46) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL821151 | 0.86 | MAPT (0.45) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| Hydrochloric Acid SCHEMBL15380794 | 0.85 | MAPT (0.44) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| Hydrochloric Acid SCHEMBL476928 | 0.85 | MAPT (0.44) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| Hydrochloric Acid SCHEMBL29378499 | 0.85 | MAPT (0.44) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| Hydrochloric Acid SCHEMBL29488522 | 0.85 | MAPT (0.44) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL22809830 | 0.84 | ALOX15 (0.45) | MAPTALDH1A1POLBL3MBTL1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100215635-A1 | SMALL MOLECULES TO INDUCE WEIGHT LOSS OR TO REDUCE WEIGHT GAIN | KISS ZOLTAN | 2010-08-26 | — | — | US | claimed |
| US-20100022617-A1 | COMPOSITIONS AND METHODS TO CONTROL ABNORMAL CELL GROWTH | CANCURE LABORATORIES, LLC (US) | 2010-01-28 | — | — | US | claimed |
| WO-2009015207-A1 | SMALL MOLECULES FOR THE PROTECTION OF PANCREATIC CELLS | ZOLTAN LABORATORIES LLC (US) | 2009-01-29 | — | — | WO | claimed |
| WO-2008118164-A1 | COMPOUNDS TO PROMOTE REGENERATION OF BONE MARROW | ZOLTAN LABORATORIES LLC (US) | 2008-10-02 | — | — | WO | claimed |
| US-20080234234-A1 | COMPOUNDS TO PROMOTE REGENERATION OF BONE MARROW | ZOLTAN LABORATORIES, LLC (US) | 2008-09-25 | — | — | US | claimed |
| US-20100215635-A1 | SMALL MOLECULES TO INDUCE WEIGHT LOSS OR TO REDUCE WEIGHT GAIN | KISS ZOLTAN | 2010-08-26 | — | — | US | disclosed |
| WO-2009015207-A1 | SMALL MOLECULES FOR THE PROTECTION OF PANCREATIC CELLS | ZOLTAN LABORATORIES LLC (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2009015207-A1 | SMALL MOLECULES FOR THE PROTECTION OF PANCREATIC CELLS | ZOLTAN LABORATORIES LLC (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2008118164-A1 | COMPOUNDS TO PROMOTE REGENERATION OF BONE MARROW | ZOLTAN LABORATORIES LLC (US) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100215635-A1 | SMALL MOLECULES TO INDUCE WEIGHT LOSS OR TO REDUCE WEIGHT GAIN | GPR119, FABP4, PNLIP | MAPT 3901/4885ALDH1A1 1372/4885POLB 2196/4885 |
| US-20080234234-A1 | COMPOUNDS TO PROMOTE REGENERATION OF BONE MARROW | PDGFA, BMP4, BMP2 | MAPT 4844/4885ALDH1A1 1400/4885POLB 1550/4885 |
| US-20100022617-A1 | COMPOSITIONS AND METHODS TO CONTROL ABNORMAL CELL GROWTH | ALPP, ALPG, DNTT | MAPT 1412/4885ALDH1A1 2278/4885POLB 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.