Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845870 | 0.87 | PPARA (0.44) | PPARAPPARGCYP4F2CYP4A11CYP4Z1 | |
| SCHEMBL4769424 | 0.84 | CYP4F2 (0.59) | CYP4F2CYP4A11TDP1ALOX5CYP4Z1 | |
| SCHEMBL4425984 | 0.80 | CYP4F2 (0.64) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL879289 | 0.76 | CYP4F2 (0.58) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL13104077 | 0.76 | CYP4F2 (0.58) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL317948 | 0.76 | RAB9A (0.52) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL3175607 | 0.75 | CYP4F2 (0.65) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL22070553 | 0.75 | CYP4F2 (0.76) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL2745464 | 0.75 | CYP4F2 (0.57) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL10725552 | 0.75 | CYP4F2 (0.61) | PPARAPPARGCYP4F2CYP4A11TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020445-B1 | FUSED PYRIDINE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6875761-B2 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. | 2004-10-14 | — | — | US | disclosed |
| US-6790844-B2 | MUSCLE RELAXANTS; ANTISEROTONINE AGENT | EISAI CO., LTD (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020013460-A1 | Condensed pyridine compound | EISAI CO., LTD | 2002-01-31 | — | — | US | disclosed |
| US-6340759-B1 | ANTISPASMODIC AGENTS | EISAI CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1020445-A1 | FUSED PYRIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013460-A1 | Condensed pyridine compound | MUSK, HTR1A, PAX3 | PPARA 1247/4885PPARG 1862/4885CYP4F2 2166/4885 |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | MUSK, HTR1A, RYR1 | PPARA 3207/4885PPARG 2582/4885CYP4F2 2733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.