Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776675 | 0.88 | HTR7 (0.47) | KMT2AMAPTALDH1A1HTTNPSR1 | |
| SCHEMBL4774593 | 0.85 | ALDH1A1 (0.44) | KMT2AMAPTMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4795522 | 0.84 | PIK3CA (0.53) | MAPTALDH1A1L3MBTL1PIK3CASMN1; SMN2 | |
| SCHEMBL3718892 | 0.78 | KMT2A (0.62) | KMT2AMAPTMEN1ALDH1A1PIK3CA | |
| SCHEMBL4793423 | 0.75 | PIK3CA (0.43) | L3MBTL1PIK3CAHTTLMNAPOLB | |
| SCHEMBL4779650 | 0.75 | MAPT (0.46) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31549907 | 0.74 | KMT2A (0.65) | KMT2AMAPTMEN1ALDH1A1PIK3CA | |
| SCHEMBL4778477 | 0.74 | MEN1 (0.45) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4781142 | 0.73 | ALDH1A1 (0.48) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4774611 | 0.70 | LTB4R (0.47) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |