Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774559 | 0.85 | KMT2A (0.48) | ALDH1A1LMNAMAPTHTTCYP2C19 | |
| SCHEMBL4776675 | 0.85 | HTR7 (0.47) | ALDH1A1MAPTHTTCYP2C19CYP1A2 | |
| SCHEMBL4778477 | 0.79 | MEN1 (0.45) | ALDH1A1LMNAMAPTHTTSIGMAR1 | |
| SCHEMBL4779650 | 0.74 | MAPT (0.46) | ALDH1A1LMNAMAPTSIGMAR1KMT2A | |
| SCHEMBL4781142 | 0.71 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTHTTSIGMAR1 | |
| SCHEMBL4774611 | 0.69 | LTB4R (0.47) | ALDH1A1MAPTKMT2AMEN1PSD | |
| SCHEMBL4776747 | 0.69 | PKM (0.43) | ALDH1A1LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL4795522 | 0.69 | PIK3CA (0.53) | ALDH1A1LMNAMAPTHTTSIGMAR1 | |
| SCHEMBL4776218 | 0.69 | CYP19A1 (0.42) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL4779144 | 0.66 | MEN1 (0.47) | ALDH1A1LMNAMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |