Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.47 |
| ▸ | EIF4A1 | P60842 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776218 | 0.89 | CYP19A1 (0.42) | LTB4REIF4A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4779682 | 0.85 | PLA2G2A (0.41) | LTB4REIF4A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4774672 | 0.84 | NOS3 (0.43) | LTB4RMEN1MAPTKMT2ARAB9A | |
| SCHEMBL4779677 | 0.84 | EIF4A1 (0.43) | LTB4REIF4A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4774562 | 0.82 | CYP19A1 (0.42) | LTB4RCYP19A1CYP11B1CYP11B2MEN1 | |
| SCHEMBL4779671 | 0.78 | EIF4A1 (0.40) | LTB4REIF4A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4779650 | 0.77 | MAPT (0.46) | LTB4REIF4A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4778477 | 0.76 | MEN1 (0.45) | LTB4REIF4A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4778107 | 0.75 | LTB4R (0.48) | LTB4RCYP19A1CYP11B1CYP11B2MEN1 | |
| SCHEMBL4881501 | 0.74 | PTGIR (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |