Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 7/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826368 | 0.91 | ALDH1A1 (0.38) | ALDH1A1POLBMAPTTNFMTNR1A | |
| SCHEMBL4768461 | 0.83 | ALDH1A1 (0.38) | ALDH1A1POLBMAPTTNFMTNR1A | |
| SCHEMBL4640769 | 0.83 | CA2 (0.44) | ALDH1A1POLBMAPTTNFMTNR1A | |
| SCHEMBL4889652 | 0.82 | CNR2 (0.41) | ALDH1A1POLBMAPTTNFLMNA | |
| SCHEMBL4640355 | 0.81 | MTNR1A (0.49) | ALDH1A1POLBMAPTTNFMTNR1A | |
| SCHEMBL4777107 | 0.79 | TNF (0.36) | ALDH1A1MAPTTNFCA2MEN1 | |
| SCHEMBL4913399 | 0.76 | NPC1 (0.47) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4893401 | 0.76 | CNR2 (0.39) | ALDH1A1POLBMAPTTNFMTNR1A | |
| SCHEMBL4916141 | 0.74 | NPC1 (0.48) | ALDH1A1POLBMAPTTNFMTNR1A | |
| SCHEMBL4638928 | 0.74 | TRPM5 (0.35) | ALDH1A1MAPTTNFLMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945304-A2 | IMIDAZO-PYRIDINE CONTAINING BETA AGONISTS, METHOD FOR PRODUCING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007048843-A2 | IMIDAZO-PYRIDINE CONTAINING BETA AGONISTS, METHOD FOR PRODUCING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |