Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 3/20 | 0.39 |
| ▸ | CPT1A | P50416 | 3/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726619 | 0.88 | DAGLB (0.42) | GRM5CPT2CPT1ACPT1BPRMT5 | |
| SCHEMBL4726621 | 0.88 | DAGLB (0.42) | GRM5CPT2CPT1ACPT1BPRMT5 | |
| SCHEMBL4776201 | 0.84 | ROCK2 (0.42) | FABP4 | |
| SCHEMBL4776197 | 0.84 | ROCK2 (0.42) | FABP4 | |
| SCHEMBL4777579 | 0.82 | HSD17B2 (0.43) | FABP4KDM4E | |
| SCHEMBL5230465 | 0.80 | FAAH (0.43) | KDM4E | |
| SCHEMBL8224325 | 0.79 | PRMT5 (0.37) | PIM2HDAC3HDAC1HDAC2PRMT5 | |
| SCHEMBL4781860 | 0.78 | DAGLB (0.46) | CPT2CPT1ACPT1BKDM4E | |
| SCHEMBL4781855 | 0.78 | DAGLB (0.46) | CPT2CPT1ACPT1BKDM4E | |
| SCHEMBL3076594 | 0.76 | LMNA (0.44) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |