Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197772 | 0.91 | P2RX3 (0.37) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL23008569 | 0.91 | P2RX3 (0.37) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL18612435 | 0.91 | P2RX3 (0.37) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28579733 | 0.88 | NR1H2 (0.36) | FKBP1AALDH1A1HSD17B10P2RX3CYP1A2 | |
| SCHEMBL25217657 | 0.88 | NR1H2 (0.36) | FKBP1AALDH1A1HSD17B10P2RX3CYP1A2 | |
| SCHEMBL5133260 | 0.86 | FKBP1A (0.41) | FKBP1AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25273988 | 0.85 | HSD17B10 (0.39) | ALDH1A1HSD17B10CYP1A2POLBCYP3A4 | |
| SCHEMBL25273987 | 0.85 | HSD17B10 (0.39) | ALDH1A1HSD17B10CYP1A2POLBCYP3A4 | |
| SCHEMBL5133262 | 0.83 | RAB9A (0.37) | FKBP1AALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL706992 | 0.80 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891078-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006125974-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |