Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725768 | 0.86 | MAPT (0.51) | LMNASMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL4728262 | 0.85 | DRD2 (0.46) | LMNASMN1; SMN2ALDH1A1GLAMAPT | |
| SCHEMBL4730511 | 0.85 | FFAR1 (0.44) | LMNAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL4727610 | 0.85 | UCHL1 (0.51) | LMNASMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL4728012 | 0.85 | CES1 (0.48) | LMNASMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL4729811 | 0.85 | ALDH1A1 (0.50) | LMNAALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL4726510 | 0.84 | CNR2 (0.49) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4728036 | 0.83 | DRD3 (0.42) | LMNASMN1; SMN2ALDH1A1GLAMAPT | |
| SCHEMBL4726548 | 0.83 | CRHBP (0.48) | LMNASMN1; SMN2ALDH1A1MAPTCYP1A2 | |
| SCHEMBL4725454 | 0.83 | DRD3 (0.57) | LMNASMN1; SMN2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |