Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.52 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782085 | 0.81 | BCAT1 (0.49) | SLC40A1BCAT1MEN1KMT2AMAPT | |
| SCHEMBL4779959 | 0.74 | KDM4E (0.50) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL6410631 | 0.70 | ITK (0.55) | SLC40A1BCAT1MEN1KMT2AMAPT | |
| SCHEMBL7197593 | 0.69 | SLC40A1 (1.00) | SLC40A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL4796043 | 0.67 | ALDH1A1 (0.51) | BCAT1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL38662886 | 0.67 | POLB (0.65) | SLC40A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL1429201 | 0.67 | NPC1 (1.00) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL7245923 | 0.66 | CA2 (0.65) | BCAT1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL8752407 | 0.66 | LMNA (0.71) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL8752442 | 0.66 | LMNA (0.71) | MEN1KMT2AMAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025526-A1 | INDOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-03-06 | — | — | WO | disclosed |