Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782093 | 0.86 | NPC1 (0.48) | CNR2NPC1CNR1ALDH1A1PKM | |
| SCHEMBL4783496 | 0.86 | NPC1 (0.46) | CNR2NPC1ALDH1A1PKMGBA1 | |
| SCHEMBL4781473 | 0.86 | SFRP1 (0.46) | HTR6 | |
| SCHEMBL4782615 | 0.85 | NPC1 (0.46) | CNR2NPC1ALDH1A1PKMGBA1 | |
| SCHEMBL4782077 | 0.83 | NPC1 (0.44) | NPC1ALDH1A1PKMGBA1HTR6 | |
| SCHEMBL4780971 | 0.79 | BRD4 (0.45) | NPC1HTR6 | |
| SCHEMBL4783275 | 0.78 | SMN1; SMN2 (0.49) | CNR2NPY5RHTR6 | |
| SCHEMBL4782672 | 0.78 | ALDH1A1 (0.37) | ALDH1A1PKMHTR6 | |
| SCHEMBL4781949 | 0.78 | SFRP1 (0.38) | HTR6 | |
| SCHEMBL4780921 | 0.78 | SFRP1 (0.48) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |