Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.33 |
| ▸ | DDT | P30046 | 2/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784000 | 0.90 | DDT (0.34) | DDTMIF | |
| SCHEMBL4778554 | 0.85 | DDT (0.42) | DDT | |
| SCHEMBL4779207 | 0.83 | NR1I2 (0.38) | DDTMIFACKR3 | |
| SCHEMBL4782091 | 0.80 | BRAF (0.32) | DDT | |
| SCHEMBL4779088 | 0.79 | DDR2 (0.38) | — | |
| SCHEMBL4780120 | 0.79 | DDR1 (0.35) | — | |
| SCHEMBL4778561 | 0.77 | DDT (0.45) | DDT | |
| SCHEMBL4779210 | 0.76 | TEK (0.41) | DDTMIF | |
| SCHEMBL4783774 | 0.76 | NR1I2 (0.36) | — | |
| SCHEMBL4779766 | 0.76 | NR1I2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |