Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 9/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | DDT | P30046 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782092 | 0.92 | BRAF (0.34) | BRAFHTR1DSLC6A4DDTMAPT | |
| SCHEMBL4778554 | 0.83 | DDT (0.42) | DDT | |
| SCHEMBL4779207 | 0.81 | NR1I2 (0.38) | DDT | |
| SCHEMBL4783994 | 0.80 | EGFR (0.33) | DDT | |
| SCHEMBL4780120 | 0.79 | DDR1 (0.35) | BRAF | |
| SCHEMBL4779088 | 0.78 | DDR2 (0.38) | BRAF | |
| SCHEMBL4778561 | 0.75 | DDT (0.45) | DDTTP53 | |
| SCHEMBL4783774 | 0.75 | NR1I2 (0.36) | — | |
| SCHEMBL4779210 | 0.75 | TEK (0.41) | BRAFDDT | |
| SCHEMBL4779766 | 0.74 | NR1I2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |