SCHEMBL4786240

SCHEMBL4786240

N=C(CC(O)C(=O)OC(=O)CBr)OC(=O)CBr

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9980489 0.82 NAAA (0.35) ALDH1A1CYP2C19
SCHEMBL6025638 0.81
SCHEMBL23355066 0.78 KDM2A (0.33)
SCHEMBL18048859 0.78 MGAM (0.39)
SCHEMBL4969192 0.75 LMNA (0.37) ALDH1A1
SCHEMBL6767253 0.75 TSHR (0.40)
SCHEMBL4441021 0.74 ALDH1A1 (0.34) ALDH1A1
SCHEMBL23111822 0.74 TSHR (0.39) ALDH1A1
SCHEMBL669686 0.74 SMN1; SMN2 (0.31)
SCHEMBL868200 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008103319-A2 COMPOUNDS AND METHODS FOR USE IN DETECTING GABAPENTIN ARK DIAGNOSTICS, INC. (US) 2008-08-28 WO disclosed
EP-1756570-A4 IMMUNOASSAYS FOR BUPRENORPHINE AND NORBUPRENORPHINE DADE BEHRING INC (US) 2008-05-21 EP disclosed
EP-1756570-A2 IMMUNOASSAYS FOR BUPRENORPHINE AND NORBUPRENORPHINE DADE BEHRING INC. (US) 2007-02-28 EP disclosed
WO-2005103697-A2 IMMUNOASSAYS FOR BUPRENORPHINE AND NORBUPRENORPHINE DADE BEHRING INC. (US) 2005-11-03 WO disclosed