SCHEMBL669686

SCHEMBL669686

N=C(CC(O)C(=O)OC(=O)O)OC(=O)O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL23748030 0.79 SRD5A2 (0.39) SMN1; SMN2
SCHEMBL6059544 0.77 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL4326668 0.77 ALDH1A1 (0.36)
SCHEMBL5877940 0.77 ALOX15 (0.30)
SCHEMBL868200 0.77
SCHEMBL9980489 0.75 NAAA (0.35)
SCHEMBL23355066 0.75 KDM2A (0.33) SMN1; SMN2
SCHEMBL2726401 0.74 RECQL (0.30)
SCHEMBL4786240 0.74 TRPA1 (0.34)
SCHEMBL6025638 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001062827-A2 N-MALEIMIDYL POLYMER DERIVATIVES SHEARWATER CORPORATION (US) 2001-08-30 WO claimed
EP-3946460-B1 IMPROVED CONJUGATION LINKERS PROLYNX LLC (US) 2026-05-20 EP disclosed
US-20260007768-A1 CONJUGATION LINKERS PROLYNX LLC (US) 2026-01-08 US disclosed
EP-4587583-A1 COVALENTLY MODIFIED TEMPLATE-INDEPENDENT DNA POLYMERASE AND METHODS OF USE THEREOF The Charles Stark Draper Laboratory, Inc. (US) 2025-07-23 EP disclosed
US-12364771-B2 Conjugation linkers PROLYNX LLC (US) 2025-07-22 US disclosed
US-20240181397-A1 HIGH-THROUGHPUT MICROEMULSIFICATION MEMBRANE PROLYNX LLC (US) 2024-06-06 US disclosed
WO-2024059703-A1 COVALENTLY MODIFIED TEMPLATE-INDEPENDENT DNA POLYMERASE AND METHODS OF USE THEREOF THE CHARLES STARK DRAPER LABORATORY, INC. (US) 2024-03-21 WO disclosed
EP-4308649-A2 HIGH-THROUGHPUT MICROEMULSIFICATION MEMBRANE Prolynx LLC (US) 2024-01-24 EP disclosed
US-20230348547-A1 MODIFIED BOVINE G-CSF POLYPEPTIDES AND THEIR USES AMBRX INC (US) 2023-11-02 US disclosed
WO-2023091618-A1 COMPOSITIONS AND METHODS FOR DETECTION OF OVARIAN CANCER MERCY BIOANALYTICS, INC. (US) 2023-05-25 WO disclosed
WO-2003037384-A2 POLYMER CONJUGATES OF PROTEIN KINASE C INHIBITORS NEKTAR THERAPEUTICS AL, CORPORATION (US) 2003-05-08 WO disclosed
US-20030066988-A1 Malononitrile-derivative anion salts, and their uses as ionic conducting materials MICHOT CHRISTOPHE (FR) 2003-04-10 US disclosed
EP-1259562-A1 STERICALLY HINDERED DERIVATIVES OF WATER SOLUBLE POLYMERS Shearwater Corporation (US) 2002-11-27 EP disclosed
WO-2002065963-A1 BIODEGRADABLE CATIONIC COPOLYMERS OF POLY(ALKYLENIMINE) AND POLY(ETHYLENE GLYCOL) FOR THE DELIVERY OF BIOACTIVE AGENTS EXPRESSION GENETICS, INC. (US) 2002-08-29 WO disclosed
WO-2002040058-A2 HYDROXYAPATITE-TARGETING POLY(ETHYLENE GLYCOL) AND RELATED POLYMERS SHEARWATER CORPORATION (US) 2002-05-23 WO disclosed
US-6333425-B1 IONIC COMPOUNDS DERIVED FROM MALONONITRILE IN WHICH ANIONIC CHARGE IS DELOCALIZED; EXCELLENT PROPERTIES OF SOLUBILITY AND DISSOCIATION HYDRO-QUEBEC (CA) 2001-12-25 US disclosed
WO-2001062827-A2 N-MALEIMIDYL POLYMER DERIVATIVES SHEARWATER CORPORATION (US) 2001-08-30 WO disclosed
WO-2001046291-A1 STERICALLY HINDERED DERIVATIVES OF WATER SOLUBLE POLYMERS SHEARWATER CORPORATION (US) 2001-06-28 WO disclosed
EP-1105730-A1 ENZYME INHIBITION IMMUNOASSAY Roche Diagnostics Corporation (US) 2001-06-13 EP disclosed
WO-2001001135-A1 ENZYME INHIBITION IMMUNOASSAY ROCHE DIAGNOSTICS CORPORATION (US) 2001-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348547-A1 MODIFIED BOVINE G-CSF POLYPEPTIDES AND THEIR USES CSF3R, GMFG, HDGF SMN1; SMN2 2386/4885
US-20260007768-A1 CONJUGATION LINKERS OGFR, SLC43A1, ILK SMN1; SMN2 3755/4885
US-12364771-B2 Conjugation linkers DNPEP, FGB, VIP SMN1; SMN2 3605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.