SCHEMBL868200

SCHEMBL868200

N=C(CC(O)C(=O)OC(=O)Cl)OC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL669686 0.77 SMN1; SMN2 (0.31)
SCHEMBL5877940 0.75 ALOX15 (0.30)
SCHEMBL4326668 0.75 ALDH1A1 (0.36)
SCHEMBL18725980 0.75
SCHEMBL9980489 0.73 NAAA (0.35)
SCHEMBL4441021 0.73 ALDH1A1 (0.34)
SCHEMBL4786240 0.72 TRPA1 (0.34)
SCHEMBL6025638 0.72
SCHEMBL5670120 0.71 TSHR (0.37)
SCHEMBL23355066 0.69 KDM2A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013016120-A1 PEDERIN AND PSYMBERIN AGENTS UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2013-01-31 WO claimed
WO-2011003766-A1 BIODEGRADABLE COPOLYMER COMPRISING AMYLOPECTIN OR GLYCOGEN SUITABLE FOR DELIVERING NUCLEIC ACID MATERIALS INTO CELLS UNIVERSITY OF ROSTOCK (DE) 2011-01-13 WO claimed
US-12280021-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2025-04-22 US disclosed
WO-2024110839-A2 IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATED CAPSULAR SACCHARIDE ANTIGENS AND USES THEREOF PFIZER INC. (US) 2024-05-30 WO disclosed
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2023-11-23 US disclosed
WO-2023135515-A1 IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATED CAPSULAR SACCHARIDE ANTIGENS AND USES THEREOF PFIZER INC. (US) 2023-07-20 WO disclosed
WO-2023086983-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX, INC. (US) 2023-05-19 WO disclosed
US-11576876-B2 Affinity Medicant Conjugate AF CHEMICALS, LLC (US) 2023-02-14 US disclosed
US-11241398-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2022-02-08 US disclosed
US-20220008361-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2022-01-13 US disclosed
US-11191673-B2 Closure tape dispenser COVIDIEN LP (US) 2021-12-07 US disclosed
EP-1098667-A4 CHELATING SYSTEMS FOR USE IN THE DELIVERY OF COMPOUNDS TO CELLS MIRUS CORP (US) 2002-09-11 EP disclosed
EP-1098632-A4 CHARGE REVERSAL OF POLYION COMPLEXES MIRUS CORP (US) 2002-09-04 EP disclosed
WO-2001049841-A1 POLYAMPHOLYTES FOR DELIVERING POLYIONS TO A CELL MIRUS CORPORATION (US) 2001-07-12 WO disclosed
EP-1098632-A1 CHARGE REVERSAL OF POLYION COMPLEXES Mirus Corporation (US) 2001-05-16 EP disclosed
EP-1098667-A1 CHELATING SYSTEMS FOR USE IN THE DELIVERY OF COMPOUNDS TO CELLS Mirus Corporation (US) 2001-05-16 EP disclosed
EP-1042454-A1 MODIFIED ENZYMES COMPRISING A POLYANIONIC DOMAIN NOVO NORDISK A/S (DK) 2000-10-11 EP disclosed
WO-2000003694-A1 CHARGE REVERSAL OF POLYION COMPLEXES MIRUS CORPORATION (US) 2000-01-27 WO disclosed
WO-2000003738-A1 CHELATING SYSTEMS FOR USE IN THE DELIVERY OF COMPOUNDS TO CELLS MIRUS CORPORATION (US) 2000-01-27 WO disclosed
WO-1999033957-A1 MODIFIED ENZYMES COMPRISING A POLYANIONIC DOMAIN NOVO NORDISK A/S (DK) 1999-07-08 WO disclosed