Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15772291 | 0.81 | HTR6 (0.56) | ALDH1A1SMN1; SMN2LMNAITGB3ITGA2B | |
| SCHEMBL4743359 | 0.79 | LMNA (0.62) | ALDH1A1SMN1; SMN2LMNAHTTITGB3 | |
| SCHEMBL4784784 | 0.78 | ITGB3 (0.56) | ALDH1A1SMN1; SMN2LMNAHTTITGB3 | |
| SCHEMBL722275 | 0.77 | SIGMAR1 (0.56) | LMNAHTR6CXCR4MEN1CHRM2 | |
| Hydrochloric Acid SCHEMBL29045124 | 0.76 | CXCR4 (0.57) | LMNAHTR6CXCR4MEN1CHRM2 | |
| SCHEMBL614784 | 0.74 | KDM4E (0.58) | ALDH1A1LMNACXCR4MEN1CHRM2 | |
| SCHEMBL15780652 | 0.74 | ALDH1A1 (0.75) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL21303998 | 0.74 | SIGMAR1 (0.59) | LMNACXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL6765737 | 0.72 | CXCR4 (0.67) | LMNACXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL15771953 | 0.72 | ALDH1A1 (0.73) | ALDH1A1LMNAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |