Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.56 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.56 |
| ▸ | MMP13 | P45452 | 5/20 | 0.54 |
| ▸ | MMP2 | P08253 | 4/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.48 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.43 |
| ▸ | LIPC | P11150 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112364 | 0.86 | MMP13 (0.51) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL6096681 | 0.81 | FPR2 (0.61) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL6097719 | 0.80 | MMP13 (0.52) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL6098631 | 0.80 | SMN1; SMN2 (0.47) | EPHX2MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL7398293 | 0.80 | MMP13 (0.55) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL6096540 | 0.80 | MMP13 (0.57) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL6094533 | 0.79 | MMP2 (0.56) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL7395651 | 0.77 | MMP13 (0.53) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL23365220 | 0.77 | EPHX2 (0.62) | FPR2PROKR1MMP13MMP2EPHX2 | |
| SCHEMBL2092945 | 0.76 | LIPE (0.61) | FPR2PROKR1MMP13MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067670-B2 | Sulfamato hydroxamic acid metalloprotease inhibitor | WARNER LAMBERT COMPANY (US) | 2006-06-27 | — | — | US | disclosed |
| US-20050049280-A1 | Sulfamato hydroxamic acid metalloprotease inhibitor | PHARMACIA CORPORATION | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049280-A1 | Sulfamato hydroxamic acid metalloprotease inhibitor | MMP14, MMP12, MMP17 | FPR2 2242/4885PROKR1 2895/4885MMP13 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.