Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787977 | 0.81 | L3MBTL1 (0.40) | ALDH1A1HPGDNPSR1TSHRLMNA | |
| SCHEMBL4788693 | 0.77 | HPGD (0.58) | ALDH1A1HPGDNPC1TSHRSMN1; SMN2 | |
| SCHEMBL4789084 | 0.74 | KDM4E (0.45) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10330511 | 0.69 | HSD17B10 (0.58) | ALDH1A1HPGDNPC1NPSR1HSD17B10 | |
| SCHEMBL7245369 | 0.67 | TSHR (0.37) | ALDH1A1NPSR1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL4212502 | 0.67 | TSHR (0.37) | ALDH1A1NPSR1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL19174932 | 0.65 | HSD17B10 (0.56) | ALDH1A1HPGDNPC1NPSR1HSD17B10 | |
| SCHEMBL16907846 | 0.63 | ALDH1A1 (0.71) | ALDH1A1HPGDNPC1NPSR1HSD17B10 | |
| SCHEMBL4222227 | 0.63 | GPR119 (0.45) | ALDH1A1NPC1LMNAL3MBTL1RAB9A | |
| SCHEMBL23536584 | 0.63 | TSHR (0.61) | ALDH1A1HPGDNPC1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130319-A2 | NOVEL N-TETRAHYDRONAPHTALENE OR N-CHROMANE CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | disclosed |