Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788693 | 0.83 | HPGD (0.58) | LMNATSHRHPGDALDH1A1POLB | |
| SCHEMBL4788901 | 0.81 | ALDH1A1 (0.48) | L3MBTL1LMNATSHRHPGDALDH1A1 | |
| SCHEMBL4213722 | 0.76 | ADRA1A (0.40) | L3MBTL1ALDH1A1POLBHTTGAA | |
| SCHEMBL6819440 | 0.76 | ADRA1A (0.40) | L3MBTL1ALDH1A1POLBHTTGAA | |
| SCHEMBL4212502 | 0.73 | TSHR (0.37) | LMNATSHRALDH1A1POLBKMT2A | |
| SCHEMBL7245369 | 0.73 | TSHR (0.37) | LMNATSHRALDH1A1POLBKMT2A | |
| SCHEMBL4786908 | 0.73 | NR1H2 (0.39) | LMNAALDH1A1POLBKMT2A | |
| SCHEMBL4750860 | 0.71 | KDM4E (0.39) | L3MBTL1LMNAALDH1A1POLBHTT | |
| SCHEMBL4750442 | 0.69 | CNR1 (0.47) | L3MBTL1LMNATP53ALOX15TSHR | |
| SCHEMBL4222227 | 0.69 | GPR119 (0.45) | L3MBTL1LMNAALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130319-A2 | NOVEL N-TETRAHYDRONAPHTALENE OR N-CHROMANE CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | disclosed |