Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 11/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731334 | 0.86 | FASN (0.63) | FASNHSD11B1TRPC6ALDH1A1POLB | |
| SCHEMBL4170797 | 0.83 | FASN (0.68) | FASN | |
| SCHEMBL14210111 | 0.77 | FASN (0.48) | FASNHSD11B1TRPC6ALDH1A1POLB | |
| SCHEMBL4735661 | 0.76 | SLC9A1 (0.57) | FASNHSD11B1TRPC6ALDH1A1POLB | |
| SCHEMBL14412855 | 0.76 | HSD11B1 (0.56) | FASNHSD11B1TRPC6ALDH1A1POLB | |
| SCHEMBL4735697 | 0.74 | LMNA (0.51) | FASNHSD11B1ALDH1A1LMNAPARP10 | |
| SCHEMBL94625 | 0.74 | HSD11B1 (0.70) | FASNHSD11B1ALDH1A1POLBGAA | |
| SCHEMBL4736927 | 0.74 | FASN (0.58) | FASNHSD11B1ALDH1A1LMNA | |
| SCHEMBL8322126 | 0.74 | QDPR (0.63) | FASNHSD11B1ALDH1A1POLBGAA | |
| SCHEMBL2636579 | 0.74 | HSD11B1 (0.61) | HSD11B1TRPC6ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |