Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.32 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3544099 | 0.89 | LMNA (0.37) | SLC7A5S1PR3GABRA1GABRG2GABRB3 | |
| SCHEMBL21702362 | 0.77 | TDP1 (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30047650 | 0.77 | TDP1 (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4796423 | 0.73 | KEAP1 (0.41) | SLC7A5S1PR3GABRA1GABRG2GABRB3 | |
| SCHEMBL27432514 | 0.72 | GABRA1 (0.39) | SLC7A5GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL21094068 | 0.71 | TDP1 (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2132762 | 0.71 | GABRG2 (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL17785020 | 0.70 | S1PR1 (0.49) | S1PR3S1PR1TDP1CA12CA1 | |
| SCHEMBL662974 | 0.70 | CES2 (0.50) | SLC7A5GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL6141564 | 0.70 | ALOX15 (0.41) | SLC7A5GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1935881-A1 | ARYL-SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-06-25 | — | — | EP | disclosed |